Open AccessCHRONIC VIRAL HEPATITIS AND INFLAMMATORY BOWEL DISEASE
Author(s) -
Г. В. Волынец,
AUTHOR_ID
Publication year - 2021
Publication title -
gepatologiâ i gastroènterologiâ
Language(s) - English
Resource type - Journals
eISSN - 2708-5309
pISSN - 2616-5546
DOI - 10.25298/2616-5546-2021-5-2-111-117
Subject(s) - medicine , inflammatory bowel disease , ulcerative colitis , immunology , disease , viral hepatitis , hepatitis c virus , virus , chronic hepatitis , hepatitis , hepatitis b virus
The article presents the results of a literature review devoted to the study of the problems of the concurrent course of inflammatory bowel diseases (IBD), which include ulcerative colitis (UC) and Crohn's disease (CD), as well as chronic viral hepatitis (CVH) - chronic hepatitis B (CHB) and chronic hepatitis C (CHC). The prevalence of CHB and CHC in IBD in different countries ranges from 1% to 9%. The clinical course of these concurrent diseases, the possibility of hepatitis B virus (HBV) and hepatitis C virus (HCV) reactivation during immunosuppressive therapy are described. Recommendations on the peculiarities of examination and management of patients with concurrent pathology of IBD and CVH are presented. The combined pathology of IBD and CVH is a significant public health problem worldwide that requires further largescale study. The use of immunosuppressive therapy for IBD can be accompanied by the activation of HBV and HCV infection, therefore, the management of such patients should occur on an individual basis.