Open AccessMACRO-ASPARTATE AMINOTRANSFERASE
Author(s) -
N. N. Silivontchik,
A. I. Lednik,
O. P. Levchuk,
Л. И. Плотникова
Publication year - 2021
Publication title -
gepatologiâ i gastroènterologiâ
Language(s) - English
Resource type - Journals
eISSN - 2708-5309
pISSN - 2616-5546
DOI - 10.25298/2616-5546-2021-5-1-25-29
Subject(s) - enzyme , macro , antibody , medicine , endocrinology , chemistry , biochemistry , immunology , computer science , programming language
Measurement of serum enzyme activity is one of the most common laboratory tests. Increased activity may be caused by abnormal enzymes with a high molecular mass, the so-called macroenzymes. Macroenzymes may be seen in healthy subjects, but can also be related to disease. Macro-aspartate aminotransferase (macro-AST) is a macroenzyme that results from an enzymatic complex consisting of AST linked to serum immunoglobulin (IgA, IgG or both). MacroAST persistence is a rare benign condition. Macro-AST is generally characterized by increased serum AST activity. The article contains analysis of literature data on patients with macro-AST.