Open AccessVIRUS-ASSOCIATED HEPATOCELLULAR LIVER CANCER
Author(s) -
О. Е. Кузнецов,
В. М. Цыркунов
Publication year - 2021
Publication title -
gepatologiâ i gastroènterologiâ
Language(s) - English
Resource type - Journals
eISSN - 2708-5309
pISSN - 2616-5546
DOI - 10.25298/2616-5546-2021-5-1-17-24
Subject(s) - liver cancer , cirrhosis , hepatocellular carcinoma , hepatocellular cancer , medicine , hepatitis c virus , cancer , epidemiology , pathological , liver disease , hepatitis b virus , virus , virology
The review presents epidemiological data on the prevalence of hepatocellular liver cancer (HCC) in different countries of the world including the Republic of Belarus, that belongs to the countries with a low prevalence of HCC. The review also contains information about variants of liver cancer associated with various hepatotropic viruses (HBV, HCV, HDV), the pathological process in which manifests itself as a mono or mixed viral infection. The mechanisms of transformation of an infectious process into an oncological one are considered. The importance of liver cirrhosis fibrosis in the development of cancer as a competing disease, the peculiarities of the morphological picture in the liver and the effect of therapy on the course of cirrhosis and hepatocellular liver cancer are emphasized.