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DIAGNOSTIC CRITERIA FOR DISSEMINATED INTRAVASCULAR COAGULATION SYNDROME AND SEPSIS-INDUCED COAGULOPATHY
Author(s) -
С. О. Тарасенко,
С. О. Дубров,
Г. Г. Суслов
Publication year - 2021
Publication title -
bìlʹ, znebolûvannâ ì ìntensivna terapìâ
Language(s) - English
Resource type - Journals
eISSN - 2520-226X
pISSN - 2519-2078
DOI - 10.25284/2519-2078.2(95).2021.238302
Subject(s) - disseminated intravascular coagulation , coagulopathy , intensive care medicine , medicine , sepsis , hyperfibrinolysis , thrombus , hemostasis , disease
The clinical manifestations of disseminated intravascular coagulation syndrome (DIC) depend on the predominance of the sum of the vectors of hypercoagulation and hyperfibrinolysis and are strongly associated with the underlying disease, against which DIC is formed. The issue of understanding the complex pathogenesis, timely diagnosis of overt DIC and early manifestations of DIC remain an urgent challenge for intensive care physicians and leading specialized societies to study the problems of hemostasis and thrombus formation. This review of the literature analyzes the pathways of DIC development, the current state of the possibility of using diagnostic markers to detect DIC, especially in sepsis. The diagnosis of sepsis-induced coagulopathy against the background of the development of multiple organ failure is highlighted as a separate issue. Diagnostic scales are presented in the form of comparative tables for a more convenient perception of information, memorization and further implementation in clinical practice.

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