Open AccessUtility of Tissue Classification in Invasive Ductal Carcinoma using Dynamic Magnetic Resonance Imaging of the Mammary Gland
Author(s) -
Yasumitsu Miyazaki,
Nobuyuki Tabata,
Yuichiro Kubo,
K. Shinozaki
Publication year - 2021
Publication title -
journal of clinical imaging science
Language(s) - English
Resource type - Journals
eISSN - 2156-7514
pISSN - 2156-5597
DOI - 10.25259/jcis_173_2020
Subject(s) - medicine , ductal carcinoma , malignancy , magnetic resonance imaging , invasive ductal carcinoma , pathology , breast cancer , invasive lobular carcinoma , cancer , carcinoma , mammary gland , dynamic contrast enhanced mri , stage (stratigraphy) , radiology , biology , paleontology
Objectives: In Japan, invasive ductal carcinomas, which account for 75% of breast cancer cases, are sub-classified as solid, tubule-forming, scirrhous, and other types based on the histopathological findings. Although time-intensity curve (TIC) analysis of magnetic resonance (MR) images has shown diagnostic ability in differentiating benign and malignant tumors, its ability to diagnose different tumor tissue types has not yet been achieved. In this study, we report a histological classification of invasive ductal carcinoma using the TIC analysis of dynamic MR images of the mammary gland. Material and Methods: A total of 312 invasive ductal carcinomas were analyzed, and each tissue type that indicated malignancy in the washout parts of the tumors was classified and characterized using the TIC. Results: The tissue was classified, and the results were then compared to the pathohistological diagnosis. Using this method, the accuracy of tissue classification by quantitative analysis of TIC-MR images was 86.9% (271/312), which was higher than that obtained by ultrasonography 68.9% (215/312). Conclusion: This method is effective for classifying tissue types in invasive ductal carcinoma.