Open AccessDifferent facets of intracranial central nervous system lymphoma and its imaging mimics
Author(s) -
Hoi Ming Kwok,
K.Y. Li,
Rois L. S. Chan,
Chi Hin Chan,
Stephen Ka Hon Wong,
Chiu Man Lee,
Lik Fai Cheng,
Johnny Ka Fai
Publication year - 2022
Publication title -
journal of clinical imaging science
Language(s) - English
Resource type - Journals
eISSN - 2156-7514
pISSN - 2156-5597
DOI - 10.25259/jcis_135_2021
Subject(s) - leptomeninges , medicine , lymphoma , central nervous system , neuroimaging , primary central nervous system lymphoma , differential diagnosis , pathology , medical diagnosis , spinal cord , psychiatry
Lymphomas of the central nervous system (CNS) are broadly classified into primary CNS lymphoma (PCNSL) and secondary CNS lymphoma (SCNSL). PCNSL refers to lymphoma restricted to the brain, leptomeninges, spinal cord, or eyes without evidence of it outside the CNS at primary diagnosis, while SCNSL refers to secondary CNS involvement by systemic lymphoma. The brain is the most common site of involvement and intracranial CNS lymphoma has a highly variable imaging appearance and varies according to the patient’s clinical profile and immunity. This pictorial essay aims to illustrate the different facets of intracranial CNS lymphomas on neuroimaging. This enables radiologists to be familiarized with their key diagnostic features and differentiate from their differential diagnoses, leading to early diagnosis, and treatment.
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