Synergistic Occurrence of EGFR, ALK, and KRAS Gene Mutations in a Patient with Non-small Cell Lung Cancer (Adenocarcinoma) | Zendy

Dinesh Chandra Doval | Zendy; Rupal Tripathi | Zendy; Kumardeep Dutta Choudhury | Zendy; Ajay Sharma | Zendy; Ullas Batra | Zendy; Anurag Mehta | Zendy; PS Choudhury | Zendy

Open Access

Synergistic Occurrence of EGFR, ALK, and KRAS Gene Mutations in a Patient with Non-small Cell Lung Cancer (Adenocarcinoma)

Author(s) -

Dinesh Chandra Doval,

Rupal Tripathi,

Kumardeep Dutta Choudhury,

Ajay Sharma,

Ullas Batra,

Anurag Mehta,

PS Choudhury

Publication year - 2019

Publication title -

indian journal of medical sciences

Language(s) - English

Resource type - Journals

eISSN - 1998-3654

pISSN - 0019-5359

DOI - 10.25259/ijms_3_2019

Subject(s) - medicine , kras , adenocarcinoma , lung cancer , malignancy , oncology , disease , chemotherapy , adenocarcinoma of the lung , cancer , lung , stage (stratigraphy) , cancer research , colorectal cancer , biology , paleontology

Lung cancer is a commonly diagnosed malignancy. Adenocarcinoma, a subgroup of non-small cell lung cancer, is the commonest form and presents in an advanced stage of the disease, leaving a limited treatment option. Response to the standard chemotherapy regimens is overall poor. We present a case of synergistic occurrence of triple gene mutations in a patient with well-diff erentiated adenocarcinoma lung treated at a tertiary cancer care center in North India.

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