Open AccessA case of disseminated subcutaneous phaeohyphomycosis caused by Exserohilum rostratum with CARD9 mutation
Author(s) -
Mayuri Kalantri,
Uday Khopkar,
Avani Shah,
Umair Ahmed Bargir,
Gouri Hule,
Manisha Madkaikar
Publication year - 2021
Publication title -
indian journal of dermatology, venereology, and leprology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.514
H-Index - 45
eISSN - 0973-3922
pISSN - 0378-6323
DOI - 10.25259/ijdvl_293_19
Subject(s) - phaeohyphomycosis , itraconazole , exserohilum , amphotericin b , dermatology , pathology , conidium , medicine , biology , antifungal , botany , blight
Phaeohypomycosis is a rare cutaneous and subcutaneous fungal infection caused by dematiaceous fungi. They have a widespread global distribution occasionally affecting humans. A 26-year-old woman presented with multiple skin lesions over her face and extremities for last 7 years, unresponsive to systemic amphotericin B and itraconazole. Further investigations revealed CARD9 mutation and phaeohyphomycosis caused by the pigmented fungus Exserohilum rosatratum . Lesions subsequently improved with oral flucytosine and itraconazole.