Open AccessAnatomic imaging study of luminal diameter of the circle of Willis in patients with ischemic stroke
Author(s) -
Samson Omini Paulinus,
Benjamin Effiong Udoh,
Samuel Archibong Efanga,
Gabriel Udo-Affah,
Eru Mba Eru,
Charles Chibunna Ani,
Ulu Ulu Okoro,
NO Egbe
Publication year - 2021
Publication title -
calabar journal of health science
Language(s) - English
Resource type - Journals
ISSN - 2636-4786
DOI - 10.25259/cjhs_50_2020
Subject(s) - circle of willis , medicine , stroke (engine) , magnetic resonance imaging , magnetic resonance angiography , ischemic stroke , angiography , ethics committee , radiology , ischemia , mechanical engineering , public administration , political science , engineering
Objectives: Stroke or cerebrovascular accident is associated with defects in the circle of Willis; the vascular network that supplies the brain. There is currently lack of literature on the involvement of the circle of Willis in patients with stroke or its association with impending stroke. The objective of the study was to evaluate luminal diameter of arteries that constitute the circle of Willis in patients with stroke using computed tomography angiography (CTA) and magnetic resonance imaging (MRI) scans. Material and Methods: Angiograms of 340 male and female patients aged 15–>75 (40.18 ± 1.1 and 43.68 ± 1.18) years with suspected stroke, referred for either brain CTA or MRI in selected hospitals/diagnostic centers in Nigeria were evaluated using RadiAnt and the MicroDicom viewer software applications. A retrospective descriptive research design was adopted with approval from the federal health research ethics committee. Direct measurement of luminal diameter of major arteries of the circle of Willis was done using SPSS version 25 at P < 0.05. Results: From the 340 images assessed, 256 (75.29%) patients had ischemic stroke with luminal diameter of arteries of the circle of Willis ranged from 1 mm to >3 mm while 84 (24.71%) patients were without stroke with luminal diameter ranged from 1 mm to 2.11 mm ( P < 0.05). Conclusion: Patients with stroke have larger luminal diameter of arteries that form the circle of Willis when compared to patients without stroke. The study has established for the 1st time, luminal diameter of circle of Willis that may be an index in the sampled Nigerian population.