Open AccessHematological Study to Effect Androgen Anabolic steroid (Dianabol) in Female Albino Rats
Author(s) -
Jenan Mahdi Ghani,
Hanan Jassim Hammod,
Haider Salih Jaffat
Publication year - 2018
Publication title -
international journal of pharmaceutical quality assurance
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.114
H-Index - 7
ISSN - 0975-9506
DOI - 10.25258/ijpqa.v9i01.11363
Subject(s) - mean corpuscular volume , mean corpuscular hemoglobin , anabolic steroid , anabolism , hemoglobin , medicine , androgen , endocrinology , mean corpuscular hemoglobin concentration , lymphocyte , physiology , hormone
The present study on the Albino female rats show the effects on blood parameters induced by repeated administration of three doses of androgenic anabolic steroid (dianabol). The animals were divided in to four groups (6 animals for each group). The first group is considered as a negative control treated with diet and water only. Second, third and fourth treatment groups gives orally pendent dianabol (10, 30 and 50) mg/kg/day respectively, and all groups quaff for 6 weeks.The result showed that significant increase`(P less than 0.05) in RBC, WBC count, HB, HG, PCV, lymphocyte, platelet count, and percentage of lymphocyte in treatment groups compared with control. The results refer that significant decrease`(P less than 0.05) in mean corposclar Hemoglobin and concentration (MCHC), while the mean of corpuscular hemoglobin(MCH) and corpuscular volume (MCV) show significant increase `(P less than 0.05) compared with control group.