Open AccessClinical and epidemiological profile of sickle cell anemia in children: an integrative review
Author(s) -
Giselle Coelho Carvalho,
Joabe Lima Araújo,
Gardênia Taveira Santos,
Romeu Alves Vieira,
Camila Cristina Bastos Silva Raposo Ramos
Publication year - 2020
Publication title -
revista eletrônica acervo saúde
Language(s) - English
Resource type - Journals
ISSN - 2178-2091
DOI - 10.25248/reas.e2774.2020
Subject(s) - medicine , sickle cell anemia , anemia , epidemiology , medline , psychological intervention , disease , pediatrics , scientific literature , psychiatry , pathology , paleontology , political science , law , biology
Objective: The aim of this study is to analyze the clinical epidemiological profile of children with sickle cell anemia published in the literature over the last ten years. Methods: It is an integrative review. To search the articles, the Virtual Health Library (VHL) was used, and the articles from the database of the Scientific and Technical Literature of Latin America and the Caribbean (LILACS) of the Medical Literature Analysis and Retrieval System Online (MEDLINE) database were selected, data from the Scientific Electronic Library Online (Scielo), with national and international publications, carried out from 2007 to 2017 through the following descriptors: Sickle Cell Anemia, Profile, Children. Results: The results revealed that brown-skinned 2 to 8 year old children with the SS type genotype were the most frequently mentioned with sickle cell anemia (SCA). Among the clinical manifestations of SCA, they indicated: the infection; acute splenic sequestration; behavioral and performance problems of social competence, pain, skin paleness, fever, weight and iron deficiency, short stature and problems prosthetics. Final considerations: It is concluded that early diagnosis and specific interventions will allow, in addition to reducing physical damage, the adoption of more proactive strategies in view of the limitations imposed by the disease.