Role of recognizing receptors in the initiation of immune inflammation in theskin of psoriasis patients | Zendy

O R Katunina | Zendy; A. V. Rezaikina | Zendy; O I Kolykhalova | Zendy

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Role of recognizing receptors in the initiation of immune inflammation in theskin of psoriasis patients

Author(s) -

O R Katunina,

A. V. Rezaikina,

O I Kolykhalova

Publication year - 2010

Publication title -

vestnik dermatologii i venerologii

Language(s) - English

Resource type - Journals

eISSN - 2313-6294

pISSN - 0042-4609

DOI - 10.25208/vdv964

Subject(s) - tlr2 , psoriasis , receptor , tlr4 , toll , immune system , inflammation , tlr9 , immunology , toll like receptor , pattern recognition receptor , medicine , innate immune system , biology , gene , gene expression , biochemistry , dna methylation

The article presents data on the pathogenetic role of Toll-like receptors in the development of immunopathological reactions in theskin. The authors examined the distribution and content of Toll-like receptors TLR2, TLR4 and TLR9 in the affected skin of psoriasispatients. They revealed a statistically significant increase in expression of Toll-like receptors TLR2 and TLR4, which can play animportant role for the formation of the inflammatory process involving cells of the adaptive immune system.

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