Open AccessSelection of drugs for treatment of gonococcal infection based on the results ofthe monitoring of N. gonorrhoeae antibiotic resistance
Author(s) -
I N Lesnaya,
В С Соломка,
Н В Фриго,
А. А. Кубанов,
S A Polevshchikova,
С. В. Сидоренко
Publication year - 2010
Publication title -
vestnik dermatologii i venerologii
Language(s) - English
Resource type - Journals
eISSN - 2313-6294
pISSN - 0042-4609
DOI - 10.25208/vdv953
Subject(s) - gonorrhea , spectinomycin , neisseria gonorrhoeae , azithromycin , penicillin , antibiotic resistance , medicine , tetracycline , antibiotics , ciprofloxacin , russian federation , microbiology and biotechnology , biology , virology , geography , human immunodeficiency virus (hiv) , regional science
The article presents recommendations for selecting drugs for treatment of gonococcal infection based on the results of themonitoring of N. gonorrhoeae antibiotic resistance in 2009 and 2005-2009. It was shown that it is not recommended to usepenicillin, tetracycline and ciprofloxacin in the territory of the Russian Federation because of the high level of N. gonorrhoeaeresistance to these drugs. The drug of choice for gonorrhea treatment in the Russian Federation is Ceftriaxon because of thehigh level of N. gonorrhoeae sensitivity (100%). It is recommended to use spectinomycin for gonorrhea treatment only in the Uraland Far Eastern Districts; azithromycin - only in the Ural and Central Districts characterized by the high level of N. gonorrhoeaesensitivity to these antimicrobial drugs, and it is necessary to use spectinomycin and azithromycin in other federal districts ofRussia only under control of determination of N. gonorrhoeae sensitivity.