Open AccessThe influence of low and moderate doses of ultraviolet irradiation produced by the UFA-1 device possessing the wavelength of 350 to 400 nm on the parameters of skin inflammation in patients suffering atopic dermatitis
Author(s) -
А. А. Кубанов,
I. N. Avdienko
Publication year - 2011
Publication title -
vestnik dermatologii i venerologii
Language(s) - English
Resource type - Journals
eISSN - 2313-6294
pISSN - 0042-4609
DOI - 10.25208/vdv932
Subject(s) - atopic dermatitis , medicine , inflammation , dermatology , interferon , irradiation , ultraviolet irradiation , immunology , physics , nuclear physics
The performed investigation has shown that there is an increase of the content of CD4+ lymphocytes and an increased expression of γ-interferon in the skin of patients with atopic dermatitis comparing to healthy volunteers. Therapy with the use of UFA-1 produced more marked levels of γ-interferon positive cells in the skin (р = 0.004) in patients with clinical recovery compared to subjects with an achieved improvement, as well as a substantial reduction of the Т-helpers level within the effected skin areas (р = 0.009).