Open AccessStudying of relationship of Histocompatibility antigens and N-acetylation phenotype in patients of Uzbek populations with psoriasis
Author(s) -
Sh.I. Ibragimov,
G T MANSUROVA,
U. A Mamatkulov,
Maruf R. Makhsudov
Publication year - 2010
Publication title -
vestnik dermatologii i venerologii
Language(s) - English
Resource type - Journals
eISSN - 2313-6294
pISSN - 0042-4609
DOI - 10.25208/vdv834
Subject(s) - phenotype , uzbek , antigen , histocompatibility , immunology , psoriasis , major histocompatibility complex , biology , human leukocyte antigen , genetics , gene , linguistics , philosophy
There studied the distribution of Histocompatibility antigens and N-acetylation phenotype in patients of Uzbek populations with psoriasis and it has been revealed, that HLA antigenes A11, A28, В5, В13 and Cw3 are antigenes of predisposition to presented disease and the individuals with slow N-acetylation phenotype prevail among them. The relationship of more frequent associated Histocompatibility antigens and N-acetylation phenotype marked by the prevalence of patients with a slow phenotype in the dermatosis has been revealed in patients of Uzbek populations with psoriasis.