Open AccessStudies of T.pallidum proteome for the purpose of improving laboratory assessments for the syphilis diagnostics
Author(s) -
С В Ротанов,
R F HAYRULIN,
Н В Фриго
Publication year - 2012
Publication title -
vestnik dermatologii i venerologii
Language(s) - English
Resource type - Journals
eISSN - 2313-6294
pISSN - 0042-4609
DOI - 10.25208/vdv691
Subject(s) - syphilis , proteome , syphilis serodiagnosis , treponema , immunology , medicine , computational biology , virology , biology , bioinformatics , human immunodeficiency virus (hiv)
The review covers problems related to the ways of development of modern methods of laboratory assessment used for syphilis diagnostics on the basis of the use of specific antigens of the pathogenic agent. Results of studies of some immune proteome proteins of T.pallidum have been provided. The data on the possibility of their use for the development of new laboratory methods based on the detection of antibodies to Т. pallidum target proteins in blood serum samples of patients with different clinical forms of syphilis.