Open AccessStudy of the genetic factors predisposing to the development of psoriasis
Author(s) -
А. А. Минеева,
O S KOZHUSHNAYA,
В. А. Волнухин,
Н В Фриго,
L F ZNAMENSKAYA,
А. А. Кубанов,
Л. Е. Мелехина
Publication year - 2012
Publication title -
vestnik dermatologii i venerologii
Language(s) - English
Resource type - Journals
eISSN - 2313-6294
pISSN - 0042-4609
DOI - 10.25208/vdv681
Subject(s) - psoriasis , locus (genetics) , epidemiology , disease , medicine , genetics , genetic epidemiology , biology , dermatology , pathology , gene
Background papers on psoriasis epidemiology, pathogenesis and genetics are presented. Special attention is given to genetic factors of the aptitude to psoriasis development. Were analysed researches, dedicated to the genome-wide screening of associations of polymorphic genetic locus with psoriasis development. Obtained results allow to reveal pathogenic psoriasis mechanisms, to forecast the character of the clinical course of the disease, as well as the efficiency of therapy and forecast the risk of psoriasis origination at patient’s relatives.