Open AccessMinocycline in acne system therapy
Author(s) -
А. В. Самцов,
Самцов Алексей Викторович
Publication year - 2020
Publication title -
vestnik dermatologii i venerologii
Language(s) - English
Resource type - Journals
eISSN - 2313-6294
pISSN - 0042-4609
DOI - 10.25208/vdv1105-2020-96-1-67-71
Subject(s) - acne , minocycline , lipophilicity , antibiotics , systemic antibiotics , medicine , benzoyl peroxide , cephalosporin , dermatology , chemistry , microbiology and biotechnology , biology , polymer , organic chemistry , polymerization
Systemic antibiotics in combination with topical retinoids and benzoyl peroxide are first-line drugs for the treatment of moderate to severe acne. The systemic antibiotic Minocycline has a wide spectrum of action against gram + and gram-organisms, including strains resistant to penicillins and cephalosporins. A pronounced bacteriostatic effect is achieved by a high level of lipophilicity, rapid penetration through the lipid layer of bacteria and intensive accumulation in the sebaceous glands. Minolexin is a highly effective and safe medication for the treatment of moderate to severe acne and can be recommended for practical use in outpatient practice.