Open AccessClinical efficacy, safety and tolerance of clindamycin phosphate gel, 1%, in the treatment of mild tomoderate acne
Author(s) -
А. В. Самцов,
А. В. Сухарев,
O I BONDAR,
А. В. Патрушев,
R. N. Nazarov,
Alena Minchenko,
А. В. Самцов,
А. В. Сухарев,
O I BONDAR,
А. В. Патрушев,
R. N. Nazarov,
Alena Minchenko
Publication year - 2011
Publication title -
vestnik dermatologii i venerologii
Language(s) - English
Resource type - Journals
eISSN - 2313-6294
pISSN - 0042-4609
DOI - 10.25208/vdv1097
Subject(s) - acne , medicine , lotion , dermatology , dermatology life quality index , adverse effect , quality of life (healthcare) , erythromycin , antibiotics , psoriasis , pharmacology , biology , microbiology and biotechnology , nursing
The authors present the results of a prospective, open-label, post-registration comparative study of the monotherapyof mild to moderate acne with an inflammatory component. 30 subjects aged 15-35 were engaged in the study.Subjects from Group 1 (n = 15) received Clindovit® in the form of 1% gel, and subjects from Group 2 (n = 15) receiveda combination of erythromycin and zinc in the form of lotion. The duration of treatment and participation in the studywas 8 weeks. Dynamics of clinical manifestations of the disease, Dermatology Life Quality Index (DLQI), Psychologicaland Social Effects of Acne (APSEA), frequency and severity of adverse events against the background of treatmentwere assessed. The results of the study enabled the investigators to make a conclusion about efficacy, safety and goodtolerance of Clindovit® gel as a monotherapy of mild to moderate acne with an inflammatory component.