Open AccessCharacteristics of the course of atopic dermatitis in children residing under conditions ofanthropogenic pollution
Author(s) -
Yu. N. Perlamutrov,
D.E. Klyuchnikova,
Yu. N. Perlamutrov,
D YE KLYUCHNIKOVA
Publication year - 2011
Publication title -
vestnik dermatologii i venerologii
Language(s) - English
Resource type - Journals
eISSN - 2313-6294
pISSN - 0042-4609
DOI - 10.25208/vdv1072
Subject(s) - atopic dermatitis , environmental health , residence , pollution , medicine , environmental pollution , environmental protection , geography , ecology , demography , biology , immunology , sociology
Goal: to assess the impact of environmentally hazardous factors on the formation of atopic dermatitis (AD) in children.Materials and methods: 108 children aged 1-18 were engaged in the study. The AD severity was analyzed based on theSCORAD index, data from the medical history and frequency of development of complications in children dependingon the place of their residence. The elemental composition of hair was analyzed to assess the impact of anthropogenicpollution on childrens organisms. The Southeastern Administrative District (SEAD), which is unfavorable in terms ofecologic environment, and Western Administrative District (WAD) in Moscow, which is free of any human-inducedpollution, were chosen as comparison areas.Results: More severe forms of AD in terms of clinical manifestations prevailed in children residing in the SEAD. The number ofexacerbations per year was three times as high as the same index in children from the WAD, and there was no trend towardsseasonality. The course of AD in children permanently residing in the district with human-induced pollution was characterized bycomplications with the accumulation of toxic elements in hair against the background of deficiency of essential elements as wellas increased elimination of calcium from organisms resulting in low adaptive regulatory mechanisms.Conclusion: when children suffering from AD reside in a highly polluted area on a regular basis, this results in chronicintoxication of their organisms with heavy metals, which leads to deficiency of essential elements, reduction of adaptivemechanisms and severe course of dermatitis.