
Current approaches to the external therapy of photodermatoses
Author(s) -
А. Н. Хлебникова,
А. Н. Хлебникова
Publication year - 2011
Publication title -
vestnik dermatologii i venerologii
Language(s) - English
Resource type - Journals
eISSN - 2313-6294
pISSN - 0042-4609
DOI - 10.25208/vdv1053
Subject(s) - dermatology , medicine , discoid lupus erythematosus , mometasone furoate , topical steroid , itching , lupus erythematosus , surgery , corticosteroid , immunology , antibody
Remedial measures for photodamages of skin are mainly aimed at elimination of inflammation and subjective sensationssuch as burning and itching. Topical corticosteroids remain leading drugs in the external therapy of phototrauma,phototoxic and photoallergic reactions. Mometasone furoate (Elocom) has high anti-inflammatory and antiallergicactivity. Moreover, the composition of the Elocom cream is based on titanium dioxide, a classical mineral screen,which makes it possible to use the Elocom cream in case of steroid-sensitive pathology under conditions of high solarexposure. The Elocom cream has been used in the monotherapy and complex treatment of solar dermatitis, actiniccheilitis, polymorphous light eruption, discoid lupus erythematosus and actinic prurigo. Regression of manifestations ofsolar dermatitis was recorded on Day 1-3 of treatment, and regression of manifestations of actinic cheilitis - duringWeek 2 of treatment. The process in case of photoallergic reactions and discoid lupus erythematosus was over duringWeek 3-4 of treatment. Substances making a part of the composition of the Elocom cream and having photoprotectiveproperties make this cream a drug of choice for its use on skin areas subject to solar exposure in case of steroidsensitivepathology including phototrauma, phototoxic and photoallergic reactions. Besides, photoprotective propertiesof the Elocom cream explain why it should be selected for treatment of steroid-sensitive dermatoses becoming moresevere or appearing after solar exposure, in case of localization of eruptions on open skin areas (face, neck, decolletearea, hands, etc.)