Open AccessModern immunochromatographic methods for determination of anti-treponema pallidum antigenantibodies
Author(s) -
С В Ротанов,
S R Osmanova,
С В Ротанов,
S R Osmanova
Publication year - 2011
Publication title -
vestnik dermatologii i venerologii
Language(s) - English
Resource type - Journals
eISSN - 2313-6294
pISSN - 0042-4609
DOI - 10.25208/vdv1029
Subject(s) - treponema , syphilis , medicine , syphilis serodiagnosis , immunology , antibody , clinical diagnosis , virology , intensive care medicine , human immunodeficiency virus (hiv)
The authors present a review of research publications about clinical significance of using modernimmunochromatographic methods for determination of anti-immunodominant antigen antibodies of syphilis pathogenTreponema pallidum.Immunochromatographic sets of chemicals proved to be convenient in use, can be used with a small amount of biologicalmaterials, do not demand any specialized medical equipment, have high sensitivity and specificity, in particular, fortests with blood serum or plasma samples; when whole blood samples are used, this reduces the method sensitivity.Immunochromatographic tests are intended for prompt express examination of the population to reveal syphilis patientsunder field conditions or at medical institutions consulting primary patients and not having their own clinical laboratories.