Open AccessCephalosporins of the third generation for the treatment of gonorrhea
Author(s) -
Н В Фриго,
И А Гучев,
С. В. Сидоренко,
I N Lesnaya,
В С Соломка,
Н В Фриго,
И А Гучев,
С. В. Сидоренко,
I N Lesnaya,
В С Соломка
Publication year - 2011
Publication title -
vestnik dermatologii i venerologii
Language(s) - English
Resource type - Journals
eISSN - 2313-6294
pISSN - 0042-4609
DOI - 10.25208/vdv1016
Subject(s) - gonorrhea , cephalosporin , cefixime , neisseria gonorrhoeae , medicine , antibiotics , drug resistance , antibiotic resistance , third generation , drug , antimicrobial , intensive care medicine , microbiology and biotechnology , pharmacology , biology , immunology , computer science , telecommunications , human immunodeficiency virus (hiv)
The article presents the data on antibiotic resistance and N. gonorrhoeae mechanisms for developing resistance toantimicrobial drugs belonging to different pharmacologic groups and applied for causal treatment of gonorrhea. Thearticle proves the key problem related to the treatment of gonococcal infection in Russia lies in the prevalence of strainsbeing resistant to most of the antibacterial drugs that used to be applied in the clinical practice on a broad scale andefficiently. So, cephalosporins of the third generation are presently the only drug type that N. gonorrhoeae remainssensitive to. Their application ensures the maximum efficacy against the gonococcal infection. According to the presentdayinternational recommendations complying with the WHO criteria as well as accumulated experience, cefixime, a drugbelonging to cephalosporins of the third generation, can be a drug of choice for the antibacterial therapy of gonorrheaalong with ceftriaxon.