Open AccessAnalysis of the neurosyphilis incidence rate and quality oflaboratory diagnostics in the russian federation
Author(s) -
Г Л Катунин,
Н В Фриго,
С В Ротанов,
Л. Е. Мелехина,
Н. В. Китаева,
I N Lesnaya,
Г Л Катунин,
Н В Фриго,
С В Ротанов,
L YE MELEKHINA,
N V Kitayeva,
I N Lesnaya
Publication year - 2011
Publication title -
vestnik dermatologii i venerologii
Language(s) - English
Resource type - Journals
eISSN - 2313-6294
pISSN - 0042-4609
DOI - 10.25208/vdv1011
Subject(s) - neurosyphilis , medicine , syphilis , russian federation , diagnostic test , incidence (geometry) , pediatrics , family medicine , human immunodeficiency virus (hiv) , physics , optics , business , economic policy
According to the analysis of the state statistical reporting, the rate of new neurosyphilis cases was growing in theRussian Federation in 1999-2009. Substantial differences in the number of detected neurosyphilis cases by differentfederal districts were established. Low-quality laboratory diagnostics was proved to be one of the factors promoting theneurosyphilis incidence rate. The quality of the neurosyphilis laboratory diagnostics was studied by means ofquestionnaires distributed among dedicated dermatovenerological medical institutions. Substantial shortcomings in theneurosyphilis laboratory diagnostics were established including absence of spinal fluid diagnostics in 17%-33% of theinstitutions and inadequate compliance with the regulatory study methods (immunofluorescence test with whole spinalfluid, microprecipitation test, cytosis and protein determination in the spinal fluid). For the purposes of optimizing theneurosyphilis diagnostics in the Russian Federation, we suggest to provide for all-round and complex examination ofpatients with suspected neurosyphilis based on the regulatory laboratory and functional diagnostics methods; it is alsorequired to make the spinal fluid examination based on the passive hemagglutination test being highly sensitive andspecific as well as having a high diagnostic efficacy for neurosyphilis a part of the standards aimed at rendering medicalaid to neurosyphilis patients.