Open AccessView of the clinic, diagnosis and treatment of familial benign pemphigus (Hailey — Hailey disease). Literature review
Author(s) -
M. V. Drozhdina,
Marianna B. Drozhdina,
С. В. Кошкин,
С. В. Кошкин
Publication year - 2018
Publication title -
vestnik dermatologii i venerologii
Language(s) - English
Resource type - Journals
eISSN - 2313-6294
pISSN - 0042-4609
DOI - 10.25208/0042-4609-2018-94-4-7-14
Subject(s) - hailey–hailey disease , pemphigus , dermatology , disease , differential diagnosis , medicine , genetic diagnosis , pathogenesis , pathology , genetics , gene , biology
The article describes modern views on predisposing factors, histological and genetic changes, the role of ATP2C1 encoding a mutant gene, localized on chromosome 3 in the pathogenesis of Hailey — Hailey disease. Diagnostic criteria, differential diagnostics with other diseases and methods of modern treatment of this disease are presented.