Open AccessUsing clobetasol propionate in the form of a shampoo for the treatment of patients suffering from psoriasis localized in the scalp area
Author(s) -
А. Л. Бакулев,
А. Л. Бакулев,
S S Kravchenya,
С С Кравченя,
И. А. Игонина,
И. А. Игонина,
Sergei R. Utz,
С. Р. Утц
Publication year - 2016
Publication title -
vestnik dermatologii i venerologii
Language(s) - English
Resource type - Journals
eISSN - 2313-6294
pISSN - 0042-4609
DOI - 10.25208/0042-4609-2016-92-3-110-116
Subject(s) - shampoo , clobetasol propionate , dermatology , scalp , itching , psoriasis , medicine , erythema , dandruff , pathology
The study involved 80 adult psoriatic patients with scalp affections at the dermatosis progressing stage. The authors compared scalp psoriasis topical treatment options such as using 0.05% clobetasol propionate in the form of a shampoo, and successive administration of the 2% salicylic acid ointment and aforesaid short-term topical product in patients with vulgar or exudative dermatoses using dynamic scores such as mPASI, DLQI and itching intensity degree. It was demonstrated that 0.05% clobetasol propionate used in the form of a shampoo is characterized by a high efficacy and safety profile for patients with vulgar or exudative psoriasis of the scalp. At the same time, in case of exudative dermatosis successive topical treatment with the use of the 2% salicylic acid ointment and 0.05% clobetasol propionate in the form of a shampoo contributes to the clearance of psoriatic foci from accumulated scales and enables a potent topical corticosteroid such as clobetasol to efficiently reduce principal clinical symptoms of scalp psoriasis such as erythema, infiltration, exfoliation and itching. Using the clobetasol shampoo reduces the scalp itching intensity as the key psoriatic symptom preventing an isomorphic reaction as a result of foci traumatization related to scratching.