Open AccessJustification of the efficacy of antibacterial therapy for the treatment of chronic endometritis
Author(s) -
Tapilskaya N.I. Tapilskaya,
Н. И. Тапильская,
S. A. Karpeyev,
С. А. Карпеев,
С. Н. Гайдуков,
С. Н. Гайдуков
Publication year - 2015
Publication title -
vestnik dermatologii i venerologii
Language(s) - English
Resource type - Journals
eISSN - 2313-6294
pISSN - 0042-4609
DOI - 10.25208/0042-4609-2015-91-2-130-138
Subject(s) - endometritis , subclinical infection , medicine , endometriosis , endometrium , infertility , fertility , pelvic inflammatory disease , sex organ , urethritis , prostatitis , gynecology , obstetrics , intensive care medicine , pregnancy , biology , prostate , population , genetics , environmental health , cancer
A review of studies on chronic endometritis enables the authors to conclude that bacterially contaminated endometrium is the reason causing reduced fertility in case of confirmed subclinical inflammation. Chronic subclinical inflammation of the endometrium is often associated with genital endometriosis, which apparently leads to abnormal uterine bleedings. The identification of a microbial agent in case of endometritis in the routine outpatient practice is not mandatory because global experience including high-level evidence-based studies confirms the expediency of an empirical therapy based on minimum clinical criteria; otherwise, there may be irreversible consequences for the reproductive system. A preventive antibacterial therapy during the pre-conception period in infertile patients suffering from recurrent miscarriages is an efficient method to prevent reproductive losses.