Open AccessJatroidaine A: a New Tetranortirucallane Type Triterpene from Jatropha multifida
Author(s) -
Fēi Li,
Liang Ma,
Jinyuan Zhang,
Xin Qiao,
Dingshan Zhang,
Dongbo Zhang
Publication year - 2021
Publication title -
records of natural produc
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.43
H-Index - 31
ISSN - 1307-6167
DOI - 10.25135/rnp.233.21.02.1968
Subject(s) - triterpene , chemistry , euphorbiaceae , stereochemistry , jatropha , botany , biochemistry , biology , medicine , alternative medicine , pathology , biodiesel , catalysis
Jatroidaine A (1), a new tetranortirucallane-type triterpene, and two known analogues (2−3) were isolated from the leaves and branches of Jatropha multifida. Their structures were fully elucidated by extensive spectroscopic methods and comparison to known compounds. The absolute configuration of 1 was assigned by single-crystal X-ray diffraction analysis. All compounds were evaluated for their anti-inflammatory and thioredoxin reductase (TrxR) inhibitory activities. Unfortunately, no significant activity was observed.