Open AccessОСОБЛИВОСТІ ТРАНСПОРТУ ЦИНКУ І КАДМІЮ ЧЕРЕЗ МЕМБРАНИ ЕРИТРОЦИТІВ ЗА ДІЇ ПІДВИЩЕНИХ КОНЦЕНТРАЦІЙ ЇХ ІОНІВ У ВОДІ
Author(s) -
V. O. Khomenchuk,
Yu. I. Senyk,
V. Z. Kurant
Publication year - 2021
Publication title -
naukovì zapiski. serìâ bìologìâ
Language(s) - English
Resource type - Journals
ISSN - 2078-2357
DOI - 10.25128/2078-2357.21.1-2.4
Subject(s) - cadmium , zinc , membrane , chemistry , carp , penetration (warfare) , acclimatization , chelation , metal ions in aqueous solution , biophysics , red blood cell , sorption , metal , nuclear chemistry , biochemistry , fish <actinopterygii> , inorganic chemistry , biology , adsorption , botany , organic chemistry , operations research , fishery , engineering
The peculiarities of Zinc and Cadmium transport through carp erythrocyte membranes in vitro after 14 acclimatization of fish to elevated concentrations of Zn2+ and Cd2+ ions were studied. It has been established, that the uptake of Zinc and Cadmium by carp erythrocytes is to a certain extent a regulated and concentration-dependent process. The uptake of Zinc and Cadmium has been shown to involve two stages: rapid sorption of metals by the membrane surface of fish erythrocytes and slower penetration through the apical membrane of red blood cells. The increase in the value of the Michaelis constant of sorption of metal ions by erythrocytes of fish acclimatized to elevated concentrations of Zn2+ and Cd2+ ions indicates a decrease in their affinity for metals, which is the adaptive response of cells to elevated concentrations of toxicants. The nature of the penetration of Zinc and Cadmium through the biological membrane of red blood cells of fish acclimatized to the action of 2 MPC of Zn2+ and Cd2+ ions is obviously the result of significant violations of cell membrane integrity, and, consequently, reduced ability to regulate and limit the flow of studied metals .