Open AccessNeurotrophic Factors in the Treatment of Acute Brain Hypoxia Secondary to Cardiac Arrest: a Case Report
Author(s) -
Danuta Węgrzyn,
A Kutwin-Chojnacka,
Jan Bilski,
K Mroszczyk,
K Węgrzyn
Publication year - 2019
Publication title -
journal of medicine and life
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.354
H-Index - 36
eISSN - 1844-3117
pISSN - 1844-122X
DOI - 10.25122/jml-2019-1007
Subject(s) - neuroprotection , cerebrolysin , piracetam , medicine , hypoxia (environmental) , amantadine , neurotrophin , neuroscience , pharmacology , anesthesia , psychology , chemistry , receptor , organic chemistry , oxygen
Finding neuroprotective agents to counteract the deleterious effects of hypoxia on neuronal cells successfully is one of the most critical targets of clinical research since preclinical studies have identified potential neuroprotective strategies. In clinical practice, amantadine and piracetam are used with reasonable success. We present the cases of three patients with acute brain hypoxia secondary to cardiac arrest, to whom Cerebrolysin was added to the standard neuroprotective treatment regimen, leading to a notable improvement in functional outcome.