Open AccessCan Surgeons Use Parathyroid Hormone Levels as Predictive Value in Parathyroid Adenomas?
Author(s) -
Merve Tokoçin,
Talar Vartanoğlu Aktokmakyan,
Ahmet Guray Durmaz,
Onur Tokoçin,
Hüseyin Bilge,
Erkan Yavuz
Publication year - 2021
Publication title -
american journal of otolaryngology and head and neck surgery
Language(s) - English
Resource type - Journals
ISSN - 2640-6640
DOI - 10.25107/2640-6640-v4-id1128
Subject(s) - parathyroidectomy , medicine , parathyroid adenoma , parathyroid hormone , adenoma , urology , predictive value , hyperparathyroidism , primary hyperparathyroidism , endocrinology , calcium
Aim: Previous studies using different methods for PTH measurement have found a mild to moderate correlation between iPTH and gland weight. The aim of this study was to describe the relationship between parathyroid hormone and parathyroid adenoma volume, in patients with parathyroid adenomas as predictive value. Material and Methods: The multicenteric study was prepared by retrospectively collecting data from 244 patients with parathyroid adenoma who underwent parathyroidectomy and followed up between 2010 and 2020. Results: Two hundred forty and four (female/male = 203/41) patients with a mean age of 51.41 [min-max: 17 to 88] years. The mean iPTH concentrations preoperatively were 584.27 ng/L [min-max: 18.9 to 5011ng/L]. The mean diameter of adenoma of patients was 2,865 mm3 [min-max: 0.119 to 42.3 mm3]. After parathyroidectomy, PTH values were reevaluated and found as 47.2 ng/L [min-max: 0.2 to 903 ng/L]. In the patients with large parathyroid adenoma volume, preoperative PTH hormone values were statistically significantly higher (p=0.001). Conclusion: Our current study found a positive association between baseline iPTH levels and adenoma weight. These results suggest that serum iPTH level may be useful in predicting parathyroid adenoma volume.