Open AccessAcute Toxicity of Cigarette from Vietnam on in vivo Model Zebrafish (Danio rerio) Larvae
Author(s) -
Kieu Kien Trung,
Nguyễn Thị Huyền Trang,
Vũ Thị Hiền,
Nguyen Lai Thanh
Publication year - 2021
Publication title -
tạp chí khoa học đại học quốc gia hà nội: khoa học tự nhiên và công nghệ (vnu journal of science:natural sciences and technology)
Language(s) - English
Resource type - Journals
eISSN - 2615-9317
pISSN - 2588-1140
DOI - 10.25073/2588-1140/vnunst.5331
Subject(s) - zebrafish , danio , acute toxicity , larva , toxicology , traditional medicine , toxicity , biology , medicine , botany , biochemistry , gene
Smoking is widely known to has a major contributor to public health issues both in worldwide and Vietnam. At the same time, Vietnam have a large number of smokers and the market is filled with diverse brand of tobacco products. In this study, we sampled 6 types of cigarette: ThangLong, Vina, Craven, Demi, Maxx and Bastos from local stores and conducted toxicological test on zebrafish larvae. Our results show that there are varied in toxicological properties of total particle matter collected from different cigarette brands in lethal and morphology effects on zebrafish embryos. LC50 of 6 brands after 96 hours of exposure were: ThangLong = 48.7 mg/L, Vina = 45.96 mg/L, Craven = 80.52 mg/L, Demi = 30.91 mg/L, Maxx = 83.54 mg/L and Bastos = 74.92 mg/L. They are lower than 100 mg/L, which put them under Category 2 and 3 in the GHS classification criteria for acute toxicity.