Open AccessThe rationale for the effectiveness of enteral nutrition in treatment of patients with liver disease
Author(s) -
С. С. Бацков,
А В Гордиенко,
Elena D. Pyatibrat
Publication year - 2019
Publication title -
mediko-biologičeskie i socialʹno-psihologičeskie problemy bezopasnosti v črezvyčajnyh situaciâh
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.147
H-Index - 2
eISSN - 2541-7487
pISSN - 1995-4441
DOI - 10.25016/2541-7487-2019-0-1-29-34
Subject(s) - medicine , enteral administration , parenteral nutrition , gastroenterology , liver disease , albumin , body mass index , intensive care medicine
Relevance. The high incidence of diseases of the liver and other organs of digestion in employees of State Fire Service of EMERCOM of Russia results from exposure to harmful chemical factors when performing professional tasks. Currently, the growing interest of the medical scientific community and practitioners is the nutritional support for the treatment of diseases of the digestive system. Therefore, the study aimed at substantiating the effectiveness of nutritional support in the treatment of liver diseases is certainly relevant. Intention . To scientifically substantiate effectiveness of enteral nutrition in the treatment of patients with liver diseases. Method. From 2015 to 2018, 237 patients, middle-aged men (56.4 ± 9.4) years, with liver diseases and trophic insufficiency of moderate severity were examined. All subjects were divided into 2 groups, the first group consisted of 121 people receiving enteral nutrition with Nutricomp HEPA liquid, the second group consisted of 116 people treated without enteral support. To assess the effectiveness of enteral nutrition in the treatment of liver diseases, the following were analyzed: trophological status, biochemical parameters of the protein fraction of peripheral blood, proteins of the blood coagulation system and the activity of transaminases. The indicators of self-assessment of quality of life before and after treatment were also analyzed. Results and Discussion . Nutraceuticals, compared to no enteral nutrition, significantly reduced the concentrations of ammonia, increased concentrations of albumin, product of protein metabolism, indicators of blood coagulation and the activity of transaminases. They have significantly increased body mass index, and body mass deficit decreased. After treatment with enteral nutrition in patients, self-assessment of quality of life was significantly higher than in the group not receiving enteral nutrition. Conclusion. Thus, the use of nutraceuticals for enteral support of patients with reduced trophological status can significantly improve the effectiveness of therapy, promotes faster recovery and reduces time spent in hospital.