Open AccessGlycated hemoglobin measurements at three, 12 and 24 months postpartum after gestational diabetes
Author(s) -
Kristen I. Barton,
Lois Donovan,
Isabelle Giroux,
David L. Miller,
Michelle F. Mottola,
Ruth McManus
Publication year - 2019
Publication title -
clinical and investigative medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.391
H-Index - 47
eISSN - 1488-2353
pISSN - 0147-958X
DOI - 10.25011/cim.v42i4.33343
Subject(s) - medicine , glycated hemoglobin , gestational diabetes , diabetes mellitus , intraclass correlation , randomized controlled trial , obstetrics , randomization , pregnancy , physical therapy , gestation , type 2 diabetes , endocrinology , clinical psychology , biology , genetics , psychometrics
Purpose: To determine the associations between glycated hemoglobin (A1C) values at three, 12 and 24 months postpartum taken during the Families Defeating Diabetes trial.
Methods: The Families Defeating Diabetes trial was a randomized 12 month lifestyle intervention delivered in the first year postpartum. Women were reviewed at three, 6 12 and 24 months for body habitus, diet and lifestyle choices. Glycated hemoglobin levels were measured at three, 12 and 24 months.
Results: There were 170 randomization participants: 89 interventional (INT); and 81 control (CON). Of these 170 participants, 50 INT and 47 CON completed 12-month follow-up and 26 INT and 24 CON completed 24-month follow-up. Study outcomes did not differ between the cohorts. Combined intraclass correlation coefficients for reliability of repeated results showed substantial reliability: 0.74 (95% CI 0.63, 0.83) between three and 12 month A1C; and 0.72 (95% CI 0.51, 0.85) for three and 24 month A1C. Pearson correlations for three month vs 12 month A1C were r=0.745 (p