Open AccessANTIBACTERIAL, ANTIFUNGAL, ANTIOXIDANT ACTIVITY AND POLYPHENOL CONTENT OF AERIAL PARTS AND BULBS OF ALLIUM SCHUGNANICUM
Author(s) -
Saidbeg Satorov,
Fazila Mirzoeva,
Shifo Kurbonbekova,
С. Саторов,
Manizha Vakhidova,
Vyacheslav Dushenkov
Publication year - 2020
Publication title -
paëmi sino
Language(s) - English
Resource type - Journals
eISSN - 2959-6327
pISSN - 2074-0581
DOI - 10.25005/2074-0581-2020-22-1-98-105
Subject(s) - bulb , polyphenol , antioxidant , minimum inhibitory concentration , antibacterial activity , bacteria , dpph , abts , biology , food science , traditional medicine , antimicrobial , microbiology and biotechnology , botany , chemistry , biochemistry , medicine , genetics
Objective: То study of antibacterial, antifungal and antioxidant activity, and content of polyphenols in the bulb and aerial parts of an endemic species of onion A. schugnanicum. Methods: An ethanol-based extract was prepared from fresh plants. Total polyphenolic content (Folin) and ABTS antioxidant capacity assays were used to characterized extracts. Extracts obtained from bulbs, peduncle, and seeds demonstrated antibacterial activity against the reference Staphylococcus aureus (ATCC 4929), Pseudomonas aeruginosa (ATCC 4930) and Klebsiella pneumoniae (ATCC 4927) strains, as well as against the hospital strains of the same types of bacteria, i.e. strains isolated from inpatient surgical patients. Results: The study found that ethanol extracts obtained from all organs of A. schugnanicum exhibit high inhibitory activity against the hospital and reference strains. In relation to reference then to hospital strains ethanol extracts were more active. The greatest bactericidal effect on both strains was exhibited by the bulb extracts. The extracts did not inhibit the growth of Escherichia coli. Fungicidal action characterized by growth inhibition zone of bulb and seeds, respectively. The extract obtained from the peduncle of this plant exhibited smaller inhibitory activity. The antioxidant capacity of A. schugnanicum different parts are shown in all the parts had a large antioxidant activity with dominating antioxidant capacity in seeds. The highest polyphenol level was found in the bulb. Conclusions: The study showed that A. schugnanicum may be a prospective species for developing botanical therapeutics. Keywords: Allium schugnanicum, medicinal plants, growth inhibition, extracts, antioxidant activity, hospital strains of bacteria, reference strains of bacteria