Open AccessRecurrent fevers and failure to thrive in an infant
Author(s) -
David Scott,
Sarah Chan,
Johanna Chang,
Lori Broderick,
Hal M. Hoffman
Publication year - 2013
Publication title -
allergy and asthma proceedings
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.643
H-Index - 60
eISSN - 1539-6304
pISSN - 1088-5412
DOI - 10.2500/aap.2013.34.3672
Subject(s) - failure to thrive , medicine , pediatrics , intensive care medicine
We describe a 2-year old boy with consanguineous parents who recently emigrated from India and presented with oral ulcers and lymphadenopathy. He also had a history of recurrent fevers, polyarticular arthritis, chronic diarrhea, failure to thrive, and developmental delay. Infectious workup revealed herpes simplex virus 1 viremia and radiological evaluation revealed osteopenia and erosions involving multiple joints. We describe the immunologic and genetic evaluation of this patient and discuss the diagnostic and therapeutic approach to an infant with recurrent fevers.