Open AccessBiochemical and Biomechanical Myogenic Differentiation of Adipose-Derived Stem Cells for Tissue Engineering Applications
Author(s) -
Álvaro Yogi
Publication year - 2021
Publication title -
hsoa journal of stem cells research, development and therapy
Language(s) - English
Resource type - Journals
ISSN - 2381-2060
DOI - 10.24966/srdt-2060/100079
Subject(s) - tissue engineering , adipose tissue , stem cell , vascular smooth muscle , tunica media , vascular tissue , microbiology and biotechnology , smooth muscle , biology , anatomy , pathology , medicine , botany , endocrinology , genetics
Tissue engineering has shown great promise in generating vascular grafts with properties similar to that of native blood vessels. Vascular Smooth Muscle Cells (VSMC) are the main component of the vasculature tunica media. Recreation of this layer represents a major challenge in tissue engineering due to difficulties in harvesting and culturing autologous VSMC. The use of stem cells and their inherent ability to differentiate into diverse cell types, including vascular lineages, have been proposed