
In -Vivo Neuropharmacological and In-Silico Study with GABA & 5-HT to Discover Potent Anxiolytic Compound from Clerodendrum viscosum Vent. (Family: Verbenaceae)
Author(s) -
Md. Shahidul Islam
Publication year - 2020
Publication title -
journal of pharmacology, pharmaceutics, and pharmacovigilance
Language(s) - English
Resource type - Journals
ISSN - 2639-5649
DOI - 10.24966/ppp-5649/100016
Subject(s) - verbenaceae , anxiolytic , in vivo , scutellarin , pharmacology , in silico , chemistry , traditional medicine , medicine , biochemistry , biology , receptor , microbiology and biotechnology , gene
it is observed that the anxiolytic activity of Clerodendrum viscosum may be due to Scutellarin, Xylitol and 3-deoxy d-mannoic lactone either alone or synergistic effect of two or more compound interactions. So, for the molecular interaction analysis such as Scutellarin and Xylitol. Molecular docking with GABA glide score was presented as a method in this research.