Open AccessClinical Effect Of Montelukast In Asthmatic Patients With Allergic Rhinitis Treated With Intranasal Corticosteroids Or Oral Antihistamines. A Real-Life Cohort Study
Author(s) -
Vanegas Guillermo Sánchez,
Fundacion De Ciencias De Universitaria La Salud
Publication year - 2020
Publication title -
hsoa journal of pulmonary medicine and respiratory research
Language(s) - English
Resource type - Journals
ISSN - 2573-0177
DOI - 10.24966/pmrr-0177/100042
Subject(s) - montelukast , medicine , asthma , nasal administration , edema , immunology
Cysteinyl leukotrienes are responsible for common symptoms in patients with rhinitis and asthma, including edema of the airways, contraction of smooth muscle, the presence of inflammatory cells, increased blood flow, edema of the mucosa and increased mucus secretion. This situation requires a therapeutic approach that concomitantly acts on the mediators responsible for the common symptoms. The alternative that showed the greatest reduction in symptoms was the combination of intranasal corticosteroids in combination with montelukast, followed by the combination of H1 antihistamines and montelukast.