Open AccessAnalysis of DNA Methylation Sites used for Forensic Age Prediction and their Correlation with Human Aging
Author(s) -
Silva Dsbs
Publication year - 2021
Publication title -
hsoa journal of forensic, legal and investigative sciences
Language(s) - English
Resource type - Journals
ISSN - 2473-733X
DOI - 10.24966/flis-733x/100054
Subject(s) - epigenetics , dna methylation , cpg site , biology , phenotype , methylation , correlation , genetics , biological age , computational biology , genotype , dna , evolutionary biology , gene , gene expression , geometry , mathematics
Phenotype-related features, such as age, are linked to genetic components through regulatory pathways and epigenetic modifications, such as DNA methylation, are major regulators in the translation of genotype to phenotype. Age-related CpG sites have been identified and described to have predictive value in the estimation of chronological age from biological samples.