Open AccessModern chemical disinfectants and antiseptics. Part I
Author(s) -
Vasyl M. Britsun,
Natalia Simurova,
Inna Vadymivna Popova,
Oleksii V. Simurov
Publication year - 2021
Publication title -
žurnal organìčnoï ta farmacevtičnoï hìmìï
Language(s) - English
Resource type - Journals
eISSN - 2518-1548
pISSN - 2308-8303
DOI - 10.24959/ophcj.21.231997
Subject(s) - halogen , antiseptic , chemistry , reagent , organic chemistry , broad spectrum , antimicrobial , combinatorial chemistry , alkyl
Aim. To generalize and systematize information on the properties of modern chemical disinfectants and antiseptic agents (DA and AA).Results and discussion. The review provides generalized and systematized information on the properties of modern chemical DA and AA – alkylating reagents, aldehydes, amides, amidines, bisguanidines, dyes, halogenated reagents, halogens and their complexes, 2-nitrofuran derivatives. The classification of DA and AA by their chemical structure was carried out. The activity spectra, possible application ways and forms of DA and AA were given. Their toxicity and impact on the environment were described as well.Conclusions. On the basis of the analysis carried out it was shown that aldehydes, halogen-active compounds and halogen-containing complexes are modern effective DA and AA with a wide spectrum of biocidal action. Amides, amidines and bisguanidines are characterized by a narrow spectrum of activity. Dyes and 2-nitrofuran derivatives are old-fashioned antiseptics.