Open Access<strong>Primitive Neuroectodermal Tumor as the Second Malignant Neoplasm in a Long-term Survivor Child of Acute Lymphoblastic Leukemia: a Case Report</strong>
Author(s) -
Ao Li Zhang,
Xiao Juan Chen,
Zhan Qi Li,
Xiao Fan Zhu
Publication year - 2020
Publication title -
chinese medical sciences journal/chinese medical sciences journal
Language(s) - English
Resource type - Journals
ISSN - 1001-9294
DOI - 10.24920/003653
Subject(s) - medicine , lymphoblastic leukemia , term (time) , leukemia , neoplasm , pediatrics , oncology , pathology , physics , quantum mechanics
Acute lymphoblastic leukemia (ALL) is a common pediatric cancer. The second malignant neoplasms (SMNs) in long-term survivors of pediatric ALL are relatively rare. Herein we report a 10-year-old girl who was diagnosed as primitive neuroectodermal tumor (PNET) 5 years after the initial diagnosis of ALL with radiotherapy-free treatment. PNET is an exceedingly rare neoplasm in SMNs of survivors of childhood ALL. It is predisposed to be misdiagnosed and the pathogenesis is unclear. The outcome is poor. Long-term follow-up is necessary for the survival children of ALL.