Open AccessACUTE CORONARY SYNDROME: A SEA CHANGE IN OUR UNDERSTANDING OF PATHOGENESIS AND WAY OF TREATMENT? (PART I)
Author(s) -
V. I. Shalnev
Publication year - 2019
Publication title -
skoraâ medicinskaâ pomoŝʹ
Language(s) - English
Resource type - Journals
ISSN - 2072-6716
DOI - 10.24884/2072-6716-2019-20-2-67-73
Subject(s) - pathogenesis , acute coronary syndrome , medicine , coronary heart disease , intensive care medicine , disease , clinical trial , cardiology , immune system , bioinformatics , immunology , myocardial infarction , biology
The article highlights the hypothesis of the inflammatory pathways in pathogenesis of atherothrombosis and the conception of residual inflammatory risk in coronary heart disease patients. Modern approach to the correction of inflammatory risk by immune-modulating therapy in acute coronary syndrome setting is discussed. The results of most significant randomized clinical trials dedicated to this problem are also highlighted.