Open AccessProtein markers of mitochondria formation and alteration in patients with impaired blood circulation
Author(s) -
Е. С. Алексеевская,
А. А. Жлоба,
Т. Ф. Субботина,
Н. Д. Гаврилюк,
Т. А. Дружкова,
Е. В. Жидулева,
О. Б. Иртюга,
О. М. Моисеева
Publication year - 2015
Publication title -
učënye zapiski sankt-peterburgskogo gosudarstvennogo medicinskogo universiteta im. akad. i.p. pavlova/učënye zapiski sankt-peterburgskogo gosudarstvennogo medicinskogo universiteta imeni akademika i. p. pavlova
Language(s) - English
Resource type - Journals
eISSN - 2541-8807
pISSN - 1607-4181
DOI - 10.24884/1607-4181-2015-22-4-73-76
Subject(s) - mitochondrial biogenesis , biogenesis , peroxisome , mitochondrion , receptor , medicine , chemistry , peroxisome proliferator activated receptor , endocrinology , microbiology and biotechnology , biology , biochemistry , gene
Patients with abnormal left ventricular outflow tract had middle lactic acidemia with detected cytochrome C release into the bloodstream and liberation of protein PGC1a (peroxisome proliferator-activated receptor gamma coactivator-1alpha) with elevation its blood concentration reflecting mitochondrial biogenesis in tissues.