Open AccessSome cases of transfusion-related acute lung injury in clinical practice
Author(s) -
Б Б Баховадинов,
G. S. Ashurova,
Maxim A. Kucher,
A. Y. Tretyakova,
A. B. Khodzhiev,
R. M. Khakberdiev
Publication year - 2015
Publication title -
učënye zapiski sankt-peterburgskogo gosudarstvennogo medicinskogo universiteta im. akad. i.p. pavlova/učënye zapiski sankt-peterburgskogo gosudarstvennogo medicinskogo universiteta imeni akademika i. p. pavlova
Language(s) - English
Resource type - Journals
eISSN - 2541-8807
pISSN - 1607-4181
DOI - 10.24884/1607-4181-2015-22-3-29-34
Subject(s) - transfusion related acute lung injury , medicine , intensive care medicine , incidence (geometry) , complication , schema (genetic algorithms) , clinical practice , pathogenesis , diffuse alveolar damage , lung , immunology , acute respiratory distress , physical therapy , pulmonary edema , physics , machine learning , computer science , optics
Preparation of this publication was motivated by a desire to present contemporary authors look at one of the most important branches of critical care medicine - transfusion therapy and related complications, such as transfusion-related lung injury (TRALI). The article describes the causes, pathogenesis, diagnosis and therapy of TRALI patients in critical condition. In this article attention is paid to the diagnosis of TRALI, associated with transfusion of blood components, modern diagnosis criteria. The authors describe the clinical symptoms, treatment schema and propose prevention protocol of TRALI. In order to determine the incidence of TRALI in medical practice transfusion therapy data in 1900 patients was analyzed. The development of this complication was found in 12 patients, 5 patients had «possible TRALI», which is comparable with the literature data. In 5 patients and 11 donors at a laboratory study anti-leukocyte antibodies were found. The important role of prevention, based on the immune mechanisms of the pathogenesis of TRALI is marked.