Open AccessEnteral insufficiency syndrome: current provisions about the terminology, pathogenesis and treatment (review of literature)
Author(s) -
Shamil Aliyev,
Э. С. Алиев
Publication year - 2021
Publication title -
vestnik hirurgii im. i.i. grekova/vestnik hirurgii imeni i.i. grekova
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.136
H-Index - 7
eISSN - 2686-7370
pISSN - 0042-4625
DOI - 10.24884/0042-4625-2020-179-6-101-106
Subject(s) - enteral administration , pathogenesis , intensive care medicine , medicine , terminology , mechanism (biology) , bioinformatics , pathology , parenteral nutrition , biology , epistemology , linguistics , philosophy
An analytical review of the literature on the pathogenesis of disorders of the motor-evacuation function of the intestine, which underlies the enteral insufficiency syndrome (EIS), which develops in various acute intra-abdominal surgical diseases, is presented. On the basis of a multivariate analysis of literature data, various pathogenetic mechanisms of enteric dysfunctions caused by morphological and structural changes in the wall of the small intestine, violations of its local defense mechanisms are described. The essence of the modern concept of the pathogenesis of enteral insufficiency – enteral distress syndrome (EDS) according to the literature is presented. According to new views, EDS is a combination of various pathogenetic mechanisms that are formed as a result of dysregulation and destabilization of biological membranes of tissue structures of the intestinal wall (especially its mucous membrane) and a violation of the functional and metabolic status of the intestine, developing in acute surgical diseases of the abdominal organs. Recognition of the validity of the concept will allow unifying the terminology and creating more evidence-based and generally accepted teaching about the nature of EIS.