Open AccessExperimental perfusion device for preservation of donor’s liver
Author(s) -
Багненко Сергей Федорович,
Резник Олег Николаевич,
Скворцов Андрей Евгеньевич,
Лопота Александр Витальевич,
Грязнов Николай Анатольевич,
Харламов Вячеслав Валентинович,
Киреева Галина Сергеевна
Publication year - 2017
Publication title -
vestnik hirurgii im. i.i. grekova/vestnik hirurgii imeni i.i. grekova
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.136
H-Index - 7
eISSN - 2686-7370
pISSN - 0042-4625
DOI - 10.24884/0042-4625-2017-176-3-88-92
Subject(s) - perfusion , machine perfusion , medicine , liver transplantation , transplantation , biomedical engineering , normalization (sociology) , ischemia , computer science , surgery , cardiology , sociology , anthropology
OBJECTIVE. The authors aimed to develop complex perfusion medical device in order to successfully maintain viability of donor liver until transplantation. MATERIAL AND METHODS. Experimental perfusion device for normothermic perfusion donor’s liver was developed and tested in the Central Research and Experimental-design Institute of Robotics and Technical Cybernetics. RESULTS. The pre-clinical tests were performed on porcine liver. It was demonstrated that normothermic machine perfusion could restore liver function after 30 minutes of warm ischemia time and provide normalization of biochemical parameters of organ functioning.