Open AccessNon Cirrhotic Portal Vein Thrombosis: Diagnostic and Therapeutic Challenge
Author(s) -
Syifa Mustika,
Pratista Adi Krisna
Publication year - 2021
Publication title -
the indonesian journal of gastroenterology, hepatology, and digestive endoscopy/the indonesian journal of gastroenterology hepatology and digestive endoscopy
Language(s) - English
Resource type - Journals
eISSN - 2302-8181
pISSN - 1411-4801
DOI - 10.24871/221202179-83
Subject(s) - medicine , portal vein thrombosis , cirrhosis , portal hypertension , thrombosis , gastrointestinal bleeding , radiology , upper gastrointestinal bleeding , portal venous pressure , venous thrombosis , gastroenterology , endoscopy
Portal vein thrombosis (PVT), the second most common cause of portal hypertension, can be found in cirrhosis and non-cirrhosis patients. Various factors can cause non-cirrhosis PVT, such as biliary infection. Upper gastrointestinal bleeding without sign of liver failure, must be considered as non-cirrhosis PVT manifestation. Combining physical, laboratory, endoscopic and radiological examination is needed to establish the diagnosis of PVT. The principle of PVT management consists of 3 keypoints. They are prevention and treatment of gastrointestinal bleeding, prevention of recurrent thrombosis and portal cholangiopathy therapy. Many aspect should be considered regarding the administration of anticoagulants in PVT patients, especially chronic PVT with cavernomas.