Open AccessSupplementation of Red Bean (Phaseolus vulgaris L) Extract Decreased Malondialdehyde (MDA) Levels of Stressly Induced Activity of Male Wistar Rats (Rattus norvegicus)
Author(s) -
Gina Septivani,
Wimpie Pangkahila,
Indraguna Pinatih
Publication year - 2019
Publication title -
metamorfosa: journal of bilogical sciences/metamorfosa : journal of biological sciences
Language(s) - English
Resource type - Journals
eISSN - 2655-8122
pISSN - 2302-5697
DOI - 10.24843/metamorfosa.2019.v06.i02.p18
Subject(s) - phaseolus , malondialdehyde , overtraining , biology , oxidative stress , significant difference , zoology , traditional medicine , medicine , botany , biochemistry , athletes , physical therapy
This study aims to prove that supplementation of red bean extract (Phaseolus vulgaris L) decreased malondialdehyde (MDA) levels of stressly induced activity of male wistar rats (Rattus norvegicus). This research was an experimental with pre-test post-test control group design. The rats were randomly divides into 3 groups: negatif control group (P0), positive control group (treated with overtraining and aquades 2ml/P1), and treatment group (treated with supllementation of red bean extract 650 mg/200 g body weight and overtraining/P2). The rats were swam for 45 minutes everyday. Data were analysed by one way anova test. The study showed that MDA level pretest of the each group was 69,70±0,52 mmol/L; 70,12±0,54 mmol/L and 69,59±0,51 mmol/L respectively. MDA level posttest of the each group was 69,66±0,27 mmol/L; 90,08±0,20 mmol/L and 62,85±0,50 mmol/L respectively. From the result of this study, it can be concluded that suplementation of red bean extract (Phaseolus vulgaris L) decreased malondialdehyde (MDA) levels of stressly induced activity of male wistar rats (Rattus norvegicus).
Keyword: red bean (Phaseolus vulgaris L) extract, rats, overtraining, MDA, stress oxidative.