Open AccessProton 3D MR spectroscopy in the diagnosis of glial brain tumors
Author(s) -
A. N. Tyurina,
Igor Pronin,
Л. М. Фадеева,
А И Баталов,
Н. Е. Захарова,
А. Е. Подопригора,
Е. И. Шульц,
Valery Kornienko
Publication year - 2019
Publication title -
medicinskaâ vizualizaciâ
Language(s) - English
Resource type - Journals
eISSN - 2408-9516
pISSN - 1607-0763
DOI - 10.24835/1607-0763-2019-3-8-18
Subject(s) - malignancy , white matter , in vivo magnetic resonance spectroscopy , proton magnetic resonance , brain tumor , medicine , glial tumor , nuclear medicine , pathology , spectroscopy , glioma , nuclear magnetic resonance , radiology , magnetic resonance imaging , cancer research , physics , quantum mechanics
The purpose of this study was an assessment of the proton 3D MR spectroscopy efficacy in diagnosis of primary glial brain tumors. Material and methods . Sixty three patients aged from 20 to 60 years with primary glial brain tumors of varying degrees of malignancy were examined. The ratios of main metabolites indices were evaluated with following comparison with the metabolites obtained in gray and white matter of the opposite hemisphere.The ratios of main metabolites: Cho/Cr, NAA/Cr, Cho/NAA showed significant (p <0.005) differences in the groups of patients with low and high grade gliomas. Results. The obtained data proved the efficacy of the proton 3D MR-spectroscopy in predicting of the glial brain tumors malignancy.